Welcome to the "GeneLab Chats" series, a platform where insightful conversations unfold with the authors of GeneLab-enabled publications. Within this concise interview format, GeneLab engages with these researchers to gain a comprehensive understanding of the publication's scope and to explore the role of the GeneLab data system in facilitating their groundbreaking research. In this episode, we spotlight the newest publication led by Dr Géraldine Vitry of Staffordshire University and the International Space University.
Human presence in space is hampered by space stressors such as space radiation, microgravity, confinement, isolation, hostile conditions, and distance from Earth, that all induce physiological changes. While tissues such as muscle and liver are the most affected tissues during spaceflight, their relationship in response to space exposure have never been studied. This publication by Dr Vitry "Muscle atrophy phenotype gene expression during spaceflight is linked to a metabolic crosstalk in both the liver and the muscle in mice," explores the re-analysis of Open Science datasets (OSD-103 and OSD-168) and describes, for the first time, the relationship of the response of both mouse liver and muscle during spaceflight.
GeneLab recently spoke to Dr Vitry about this work and highlights how the GeneLab data systems and Analysis Working Groups (AWGs) enabled this reanalysis.