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Open Science Data Repository

The NASA Open Science Data Repository (OSDR) enables access to space-related data from experiments and missions that investigate biological and health responses of terrestrial life to spaceflight. The goal of OSDR is to enable multi-modal and multi-hierarchical fundamental space life science data be reused toward basic science, applied science, and operational outcomes for space exploration and knowledge discovery. These data include ‘omics, phenotypic, physiological, behavioral, hardware, environmental telemetry; raw, processed; tabular, text, code, bioimaging, and video.

Learn More About OSDR
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      Explore and Contribute

      Open Science Data Repository

      Search and upload spaceflight datasets

      Explore the Data Repository

      Submit Data to OSDR

      Have space-relevant data to submit?

      Contribute via the Submission Portal
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      Latest News
      OSDR Chats with Konstantinos Adamopoulos

      OSDR Chats with Konstantinos Adamopoulos on His Latest Publication Welcome to OSDR Chats, an interview series featuring authors of OSDR-enabled…
      GL4HS Summer 2025

      Announcing NASA’s GeneLab for High Schools (GL4HS) Program: Summer 2025 NASA’s GeneLab for High Schools (GL4HS) announces its expanded 2025…
      New NBISC Portal

      NBISC Launches New Biospecimen Portal to Accelerate Research The NASA Biological Institutional Collection (NBISC) is a biorepository of non-human samples…

      By the Numbers

      NASA Open Science Data Repositories expands scientists’ access to space-related experiments that explore the biological response of terrestrial biology to spaceflight environments. Our mission is to maximize the utilization of the valuable biological research resources and enable new discoveries.

      TODAY

      531

      Studies

      995

      Datasets

      Latest Datasets

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      OSD-792

      Transcriptomic analysis of embryonic mouse hypothalamic N38 cells exposed to high-energy protons and/or simulated microgravity. (TRANSCRIPTOMICS)

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      OSD-793

      Mission SpaceX CRS-16 RRRM-1 space flight induced skin genomic plasticity via an epigenetic trigger. (GENOMICS, TRANSCRIPTOMICS)

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      OSD-794

      Characterization of Spacesuit Associated Microbial Communities and Their Implications for NASA Missions. (GENOMICS)

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      OSD-612

      Bulk RNA sequencing and single nuclei transcriptomics and epigenomics of brain tissue from mice flown on the RR-10 mission. (TRANSCRIPTOMICS)

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      OSD-613

      Bulk RNA sequencing and single nuclei transcriptomics and epigenomics of brain tissue from mice flown on the RRRM-2 mission. (TRANSCRIPTOMICS)

      Publication Highlight

      Transcriptional response of Arabidopsis thaliana’s root-tip to spaceflight

      Plants are vital for future space missions to the Moon and Mars, providing essential life support functions. A key study explored how the root-tips of Arabidopsis thaliana respond to spaceflight, as roots are critical for nutrient absorption and stability. By analyzing gene activity under light and dark conditions across different plant genotypes, researchers identified significant stress responses, including hypoxia (low oxygen) as a major factor. These findings help us better understand how plants adapt to space, guiding improvements for future missions.

      Learn More about Publication Highlight
      A diagram illustrating a KEGG pathway
      From Figure 3 of publication “Transcriptional response of Arabidopsis thaliana root tip”

      Visualization Tools

      Data Visualization

      GeneLab’s latest software release includes a new visualization portal to interact with gene expression data from space-related omics experiments. The enhanced portal includes a new search interface, new plots and layout, and advanced settings to customize the plots.

      Go to Visualization Portal

      RadLab

      RadLab is a portal that aims to provide a single point of access to radiation telemetry data from multiple databases maintained by multiple space agencies.

      Go to RadLab Portal

      Environmental Data App (EDA)

      The Environmental Data App (EDA) is a portal where users can visualize and compare ISS (International Space Station) cabin environmental telemetry data and radiation data gathered from spaceflight missions.

      Go to EDA

      Testimonials

      Dr Emmanuel Gonzalez – McGill University

      This kind of collaboration makes open science so powerful: it pushes research further than any one team could on their own.

      Read more testimonials about Testimonials
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      Open Science Projects

      Open Science Projects primary goals aim to increase collaborative scientific data sharing, analysis, and more rapid scientific advancement.

      ALSDA

      GeneLab

      NBISC

      BSP

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