What is the AWG Symposium?
To explore deeper into space, it is crucial that we learn how our bodies change and adapt to the unique environment of space. GeneLab helps scientists understand how the fundamental building blocks of life itself – DNA, RNA, proteins, and metabolites – change from exposure to microgravity, radiation, and other aspects of the space environment. The purpose of the GeneLab Analysis Working Groups (AWGs) is to optimize the processing of raw omics data from the GeneLab repository to maximize the gain of new knowledge from such complex datasets. The Analysis Working Group (AWG) is comprised of scientists with diverse backgrounds and is subdivided into five main areas of expertise (plant, animal, microbes, multi-omics, and ALSDA). The AWG members focus on establishing consensus pipelines, discuss processed data and analyze GeneLab data that enables new discoveries.
This free virtual event is open to the public and will allow attendees an opportunity to hear about some of the exciting omics science stemming from the AWG community. The symposium will feature a keynote address from NASA Astronaut Kathleen "Kate" Rubins, and scientific presentations from invited speakers and AWG members that have expertise in data science, plant biology, systems biology, microbiology, and space medicine. If you are intrigued by the science occurring in the AWGs, then we would love for you to join! Learn more about how to join the AWGs during the event.
Who is appearing at the symposium?
Meeting Agenda Details:
10:00 AM – 10:10 AM PT: Opening Remarks—Jon Galazka, PhD (NASA Ames Research Center)
10:10 AM – 10:40 AM PT: Keynote Talk—"Conducting Research in Microgravity: A Scientist-Astronaut's Perspective"—Kathleen "Kate" Rubins (NASA Astronaut)
10:40 AM – 11:40 AM PT: GeneLab Grant Recipients
- 10:40 AM – 11:00 AM: “Plant Reactome: A knowledgebase of plant gene regulatory networks and pathways and its use for space biologists”— Sushma Naithani, PhD (Oregon State University)
- 11:00 AM – 11:20 AM: “At the Intersection: meta-analysis of transcriptomic datasets”— Sarah Wyatt, PhD (Ohio University)
- 11:20 AM – 11:40 AM: “Plant transcriptome modulation in response to microgravity”—Pankaj Jaiswal, PhD (Oregon State University)
11:40 AM – 12:30 PM PT: AWG Status Updates
- 11:40 AM – 11:50 AM: Animal AWG Update—Nathaniel Szewczyk, PhD (Ohio University)
- 11:50 AM – 12:00 PM: Microbes AWG Update—Braden Tierney, PhD (Weill Cornell Medicine)
- 12:00 PM – 12:10 PM: Multi-Omics AWG Update—Afshin Beheshti, PhD (NASA ARC and Broad Institute)
- 12:10 PM – 12:20 PM: Plant AWG Update—Colin Kruse, PhD (Lawrence Livermore National Labs)
- 12:20 PM – 12:30 PM: ALSDA AWG Update—Ryan Scott, MS (NASA Ames Research Center)
12:30 PM – 12:50 PM PT: Break
12:50 PM – 1:15 PM PT: Lightning Science Talks
- 12:50 PM – 12:55 PM: “Impact of Spaceflight on the Skin Transcriptome”—Henry Cope (University of Nottingham)
- 12:55 PM – 1:00 PM: TBD—Jaden Hastings, PhD (Weill Cornell Medicine)
- 1:00 PM – 1:05 PM: “Exploring Kidney Dysfunction in Space: Comparing Responses of Mouse Strains Using Omics”—Rebecca Finch, MS (Staffordshire University)
- 1:05 PM – 1:10 PM: “Mining the Gravity Mutants of Arabidopsis”—Emma Canaday (Ohio University)
- 1:10 PM – 1:15 PM: Q+A
1:15 PM – 2:30 PM: AWG Science Talks
- 1:15 PM – 1:30 PM: “The Matrix Meta-analysis of the first 15 AstroBotany Transcriptomes”—Richard Barker, PhD (University of Wisconsin at Madison)
- 1:30 PM – 1:45 PM: “Metagenomics at the murine host-gut microbiota interface during space flight”—Nicholas Brereton, PhD (University of Montreal)
- 1:45 PM – 2:00 PM: "Extraterrestrial gynecology: Could spaceflight increase the risk of developing cancer in female astronauts?"—Jean Calleja Agius, PhD (University of Malta)
- 2:00 PM – 2:15 PM: “Causal Diagramming in Human System Risk Management”—Erik Antonsen, PhD (Baylor College of Medicine)
- 2:15 PM – 2:30 PM: “Space life science research to predict the future of life on and beyond Earth”—Masafumi Muratani, PhD (University of Tsukuba)