Welcome to the "GeneLab Chats" series. In this brief interview style format, GeneLab speaks with authors of GeneLab-enabled publications to better understand the scope of their publication as well as how the GeneLab data system helped enabled their research. Read more information below about the publication highlighted in this series from Dr. Jamaji Nwanaji-Enwerem, from Emory University.
While many studies support the general understanding that ionizing radiation is linked to detrimental health states, its association with methylation-based markers of biological age is not well understood. A recent publication by Dr. Nwanaji-Enwerem, “In Vitro Relationships of Galactic Cosmic Radiation and Epigenetic Clocks in Human Bronchial Epithelial Cells,” is based on the reanalysis of GeneLab dataset OSD-317 and indicates that epigenetic clocks provide new evidence of methylation signatures associated with radiation exposure. Dr. Jamaji Nwanaji-Enwerem is an Adjunct Assistant Professor at Emory University’s Rollins School of Public Health, an emergency medicine resident physician at Emory School of Medicine, and he contributes to the GeneLab Analysis Working Group (AWG). GeneLab recently spoke to Dr. Nwanaji-Enwerem about this work, which highlights how the GeneLab data systems and AWGs enabled this reanalysis.