The NASA GeneLab Analysis Working Group has collaboratively generated four complementary datasets to interrogate changes to the gut microbiome of mice due to spaceflight. The four datasets use different technical approaches to determine which microbes and microbial genes are present within feces isolated from space-flown mice and corresponding ground controls.
While one of these datasets was generated by the GeneLab sample processing team, the rest were generated in collaboration with Dr. Stefan Green and Kevin Kuntsman at the University of Illinois Chicago and the GeneLab Microbial Analysis Working Group. In future work, the GeneLab Analysis Working Group will analyze this data to understand how gut microbiome may change during spaceflight as well as the relative value of each assay utilized. This will inform future data generation issues.
https://genelab-data.ndc.nasa.gov/genelab/accession/GLDS-249/
